Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/306540191?client_source=feed&format=rss
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Saturday, 18 May 2013
Friday, 17 May 2013
Real Estate Market Trends: Home Building Slows in April ...
The rate of new home construction fell 16.5 percent in the month of April, following a 7 percent increase in March, while the number of permits issued rose 14.3 percent, after declining by 3.9 percent in March, according to real estate market trends reported by the Commerce Department today.
New home construction took place at a seasonally adjusted annual rate of 853,000 in April, down considerably from the annual rate of more than 1.02 million for March, but 13.1 percent higher than the annual rate of 754,000 in April 2012, the Commerce Department reported.
The slump in new construction helped drag down stocks in morning trading, according to Bloomberg News, as the markets reacted to disappointing housing, employment and manufacturing data.
Building permits ? a forward-looking indicator of real estate market trends ? were issued at an annual rate of more than 1.01 million, an increase of 14.3 percent from the annual rate of 890,000 for March and 35.8 percent higher than the annual rate of 374,000 in April 2012.
Confidence among home builders rose in May, reversing months of declining confidence, according to real estate market trends reported yesterday by the National Association of Home Builders, a trade association based in Washington, D.C. The association?s Housing Market Index rose three points to a reading of 44 on improved perceptions of sales conditions, sales expectations and buyer traffic. Despite the increase, the index remains well below 50, a point that signals equal numbers of builders view real estate market trends as positive or negative.
Millionaire investors expect home prices to continue improving over the next one-to-two years. Click here to learn more.
U.S. home prices are forecast to rise by 2.5 percent in 2013, according to the analytics firm CoreLogic, and to keep rising by 3.9 percent a year over the next five years.
In other signs of improving real estate market trends, REITs ? or real estate investment trusts ? outperformed the S&P 500 Index in April. Click?here?to learn more.
Further indications of prevailing real estate market trends are due next week. The National Association of Realtors is scheduled to report existing homes sales data for April on Wednesday, and the Federal Housing Finance Authority will release its House Price Index for March on Thursday.
Source: http://www.millionairecorner.com/article/real-estate-market-trends-home-building-slows-april
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Target to prevent hardening of arteries identified
May 16, 2013 ? The hardening of arteries is a hallmark of atherosclerosis, an often deadly disease in which plaques, excessive connective tissue, and other changes build up inside vessel walls and squeeze off the flow of oxygen-rich blood throughout the body. Now, researchers at Sanford-Burnham Medical Research Institute have described the molecular and cellular pathway that leads to this hardening of the arteries -- and zeroed in on a particularly destructive protein called Dkk1.
Their study was published online today by Arteriosclerosis, Thrombosis, and Vascular Biology. The findings suggest that the development of drug therapies to selectively inhibit endothelial Dkk1 signaling may help limit arteriosclerotic disease.
"I think the strategy going forward is to find ways to modulate or inhibit Dkk1 function, but we're going to have to do it in a time-sensitive and cell type- specific fashion," said Dwight A. Towler, M.D., Ph.D., director of Sanford-Burnham's Cardiovascular Pathobiology Program and senior author of the study. "In diseases such as chronic renal deficiency or diabetes, where unregulated Dkk1 signaling can be destructive, it may be appropriate to restrain the action of Dkk1 for a prolonged period of time," Towler added.
When the inflammatory response goes awry
The Dkk1 protein, when functioning normally, is important for aiding in wound repair. But inflammatory responses triggered inside artery walls after the onset of hyperglycemia, and other metabolic injuries associated with diseases like diabetes, can trigger prolonged and destructive Dkk1 signaling.
Dkk1 triggers the conversion of cells that line the interior surface of artery walls, called endothelial cells, into mesenchymal cells, which can direct connective tissue formation. This process is known as the endothelial-mesenchymal transition. The resulting fibrosis inside arterial walls leads to a dangerous stiffening of vessels that increases systolic blood pressure and ultimately impairs distal blood flow.
Drug therapy strategies to target Dkk1
Drug therapies should focus on the places where Dkk1 inhibition is called for -- the arteries, in the case of atherosclerosis -- because healthy Dkk1 signaling regulates normal processes such as cartilage and joint remodeling. To enable this targeted approach, Towler said he hopes to develop a therapeutic drug that would include a Dkk1 inhibitor and a peptide -- a short chain of amino acids -- engineered to target specific vascular tissues.
Longtime Sanford-Burnham researcher and past president Erkki Ruoslahti, M.D., Ph.D., developed these homing peptides, which have been used to deliver cancer drugs to where they're most needed. "If we can target a Dkk1 antagonist to endothelial cells using the Ruoslahti peptides -- or a similar strategy -- that would be very, very powerful," Towler said.
Dkk1 is from a family of molecules that arose during the development of vertebrates and is involved in heart formation in embryos. Researchers initially thought the protein's only role was to inhibit a molecular pathway known as canonical Wnt signaling, which controls cell differentiation. However, these new data identify surprising "cross-talk" between Dkk1 and a bone-inducing pathway previously shown to promote the endothelial-mesenchymal transition.
Towler and his team will continue to study Dkk1 and Wnt signaling to identify potential drug targets to prevent the hardening of arteries in patients with atherosclerosis.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/3hENkf-vzq8/130516161700.htm
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Kennedy Center revises way honorees are selected
WASHINGTON (AP) ? The Kennedy Center for the Performing Arts has a new process to select artists who receive one of the nation's top arts prizes, the Kennedy Center Honors, after an outside group last year said Latinos have been largely excluded.
Under the revised process, the Kennedy Center will begin seeking recommendations from the public for the first time in the award's 35-year history. Recommendations can be submitted online beginning Thursday. The center will also seek more recommendations from a committee of artists.
To narrow the roster of potential honorees, the center is forming a new Special Honors Committee. Former honorees Chita Rivera and Yo-Yo Ma will serve on the panel, along with opera singer Harolyn Blackwell, dancer Damian Woetzel and two center board members, Elaine Wynn and Cappy McGarr. From there, the Kennedy Center chairman, president and award producers will create slates of potential honorees to balance the selections across artistic disciplines, and the executive committee of the center's board of trustees will make the final decision.
The Kennedy Center Honors have become a major cultural prize for excellence in dance, music, theater, movies or television. The honor includes a salute from the president and secretary of state each year, along with performances by top entertainers. The show is broadcast each December on CBS.
Last year, the National Hispanic Foundation for the Arts criticized the center, saying it has long excluded Latinos from the prize. Two of the more than 180 past honorees were Hispanics? Placido Domingo, the acclaimed Spanish tenor, and Rivera, the actress and singer of Puerto Rican descent. The group suggested potential Latino honorees could include Carlos Santana, Rita Moreno, Joan Baez, Gloria Estefan and others.
Giselle Fernandez, a former journalist who was born in Mexico and appointed by President Barack Obama to the Kennedy Center's board, said the revised process opens up a bigger universe of candidates for consideration.
"You're going to see much more diverse and expansive access to excellence in all disciplines, all realms and all communities," Fernandez said. She added that the Kennedy Center could provide a model for other organizations seeking to reflect the nation's diversity.
Beyond considering more Latinos, she said a broader selection process will be open "to all communities that perhaps didn't have access before because the process was too closed over the years." Facing criticism was uncomfortable but resulted in a better process, she said.
In January, the center announced a formal review of the Honors with an advisory panel that included Latino arts groups, such as the Latin Academy of Recording Arts and Sciences and the National Association of Latino Arts and Culture.
Kennedy Center Chairman David Rubenstein also met with Felix Sanchez of the National Hispanic Foundation for the Arts, who publicly criticized the center last year for excluding Latinos for years.
In addition to the revised selection process, the Kennedy Center said Thursday that it is committed to bolstering its track record on diversity and its relationship with the Hispanic community. The center is working to form a Latino Advisory Committee to meet quarterly, said spokesman John Dow.
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Kennedy Center Honors: www.kennedy-center.org/honors
___
Brett Zongker covers arts and culture for The Associated Press. Follow him online at https://twitter.com/DCArtBeat
Source: http://news.yahoo.com/kennedy-center-revises-way-honorees-selected-192350214.html
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See The New Google+ Photos Experience In Action, Making Your Pics Better
Google+ is getting a big update for its photos experience, which is rolling out to users now. Initial impressions show a work flow that makes it easier to tweak pictures quickly and even automatically, without requiring that you learn a huge amount about Photoshop or other editing software.Source: http://feedproxy.google.com/~r/Techcrunch/~3/57iQHsr7UzM/
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TC Makers: 3D Printing Wizards At Shapeways Show Us Their Brand New Queens Factory
It's rare to see a company that is so established yet so cutting edge as Shapeways. The company, founded in 2007 as a spin-off of Royal Philips Electronics, began as a one-off 3D printing service that offered basic plastic items for sale online. Over the years, however, the company has branched off into some amazing materials - steel, ceramic, and even sandstone - and they've already been able to support full color printing in 3D.Source: http://feedproxy.google.com/~r/Techcrunch/~3/B18iz-tVj_o/
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Thursday, 16 May 2013
Google TV officially updated to latest versions of Android and Chrome, faster updates promised going forward
It apparently wasn't big enough to garner a mention earlier today, but Google has now followed up its slew of I/O keynote announcements with the news that it's moving Google TV to the latest versions of Android (that'd be 4.2.2) and Chrome. What's more, it also says that it's "refactored" Google TV so that its OEMs can update their devices to future versions of Android faster than they're currently able to -- in a "matter of weeks rather than months," according to Google. Likewise, Chrome for Google TV will now be on the same six week upgrade cycle as its desktop counterpart going forward, and it'll also now come with support for hardware-based content protection.
As for those with existing Google TV devices, though, the company's only saying that they can expect to see updates in the "coming months." We've yet to hear from most Google TV manufacturers themselves yet, but LG has chimed in to say that it will be updating its devices to Jelly Bean sometime in the third quarter of this year. You can get a look at what the update will bring in the video after the break showing off high performance apps enabled by NDK support, and an LG remote control app that has two-handed control for games and updates reflecting the action on-screen.
Update: Some have asked what this means for the future of Flash on Google TV. We've confirmed with Google that this does mean the end of Flash on Google TV since it's no longer supported on the newer versions of Android, and the build that was in Google TV was already out of date. The update will bring more enhancements to HTML5 streaming and interactive content -- hopefully the sites some users frequent will expand their technology platforms just as quickly.
Filed under: Home Entertainment, HD, Google, LG
Source: Google TV Developers, LG
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